All Publications:

[22] The endo-lysosomal system drives lumen formation in a human epiblast model. (Rengarajan A, Wang S, Lin CW, Carleton AE, Sekulovski N, Taniguchi LE, Duncan MC, Taniguchi K.) bioRxiv. 2025.08.04.668503; PubMed

[21] CLDN10-driven lineage decision in an amnion and primordial germ cell progenitor at the amnion-epiblast boundary in primates. (Sekulovski NS, Carleton AE, Rengarajan A, Lin CW, Juga LN, Whorton AE, Schmidt JK, Golos TG, Taniguchi K.) Genome Biology. 2025; 26(1):263; PubMed

[20] Temporally resolved early bone morphogenetic protein-driven transcriptional cascade during human amnion specification. (Sekulovski NS, Wettstein JC, Carleton AE, Taniguchi LE, Ma X, Rao S, Schmidt JK, Golos TG, Lin C, Taniguchi K.) eLife. 2024; PubMed

[19] Monitoring Effects of Membrane Traffic Via Changes in Cell Polarity and Morphogenesis in Three-Dimensional Human Pluripotent Stem Cell Cysts. (Hamed MM, Taniguchi K, Duncan MC.) Methods Mol Biol. 2023;2557:83-98; PubMed

[18] Human epiblast lumenogenesis: From a cell aggregate to a lumenal cyst. (Carleton AE, Duncan MC, Taniguchi K.) Semin Cell Dev Biol. 2022 Nov;131:117-123; PubMed

[17] Spatially resolved cell polarity proteomics of a human epiblast model. (Wang S, Lin CW, Carleton AE, Cortez CL, Johnson C, Taniguchi LE, Sekulovski N, Townshend RF, Basrur V, Nesvizhskii AI, Zou P, Fu J, Gumucio DL, Duncan MC, Taniguchi K.) Sci Adv. 2021 Apr;7(17); PubMed

[16] Effect of Cell Spreading on Rosette Formation by Human Pluripotent Stem Cell-Derived Neural Progenitor Cells. (Townshend RF, Shao Y, Wang S, Cortez CL, Esfahani SN, Spence JR, O'Shea KS, Fu J, Gumucio DL, Taniguchi K.) Front Cell Dev Biol. 2020;8:588941 PMID: 33178701 PMCID: PMC7593581 11/13/2020. PubMed

[15] Opening the black box: Stem cell-based modeling of human post-implantation development. (Taniguchi K, Heemskerk I, Gumucio DL.) J Cell Biol. 2019 Feb 04;218(2):410-421; PubMed

[14] Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly. (Wotton D, Taniguchi K.) Am J Med Genet C Semin Med Genet. 2018 Jun;178(2):128-139 PMID: 29749689 PMCID: PMC6125192 SCOPUS ID: 2-s2.0-85046830932 05/12/2018. PubMed

[13] An apicosome initiates self-organizing morphogenesis of human pluripotent stem cells. (Taniguchi K, Shao Y, Townshend RF, Cortez CL, Harris CE, Meshinchi S, Kalantry S, Fu J, O'Shea KS, Gumucio DL.) J Cell Biol. 2017 Dec 04;216(12):3981-3990; PubMed

[12] A pluripotent stem cell-based model for post-implantation human amniotic sac development. (Shao Y, Taniguchi K, Townshend RF, Miki T, Gumucio DL, Fu J.) Nat Commun. 2017 Aug 08;8(1):208; PubMed

[11] Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche. (Shao Y, Taniguchi K, Gurdziel K, Townshend RF, Xue X, Yong KMA, Sang J, Spence JR, Gumucio DL, Fu J.) Nat Mater. 2017 Apr;16(4):419-425; PubMed

[10] Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l. (Anderson AE, Taniguchi K, Hao Y, Melhuish TA, Shah A, Turner SD, Sutherland AE, Wotton D.) Mol Cell Biol. 2017 Mar 01;37(5) PMID: 27956704 PMCID: PMC5311242 SCOPUS ID: 2-s2.0-85013977866 12/14/2016. PubMed

[9] Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning. (Taniguchi K, Anderson AE, Melhuish TA, Carlton AL, Manukyan A, Sutherland AE, Wotton D.) Eur J Hum Genet. 2017 Feb;25(2):208-215 PMID: 27924807 PMCID: PMC5255961 SCOPUS ID: 2-s2.0-85001838144 12/08/2016. PubMed

[8] Coordination of signaling and tissue mechanics during morphogenesis of murine intestinal villi: a role for mitotic cell rounding. (Freddo AM, Shoffner SK, Shao Y, Taniguchi K, Grosse AS, Guysinger MN, Wang S, Rudraraju S, Margolis B, Garikipati K, Schnell S, Gumucio DL) Integr Biol (Camb) 2016 Sep 12;8(9):918-28 PMID: 27476872 PMCID: PMC5021607 SCOPUS ID: 2-s2.0-84987623392 08/02/2016. PubMed

[7] Tgif1 and Tgif2 Regulate Axial Patterning in Mouse. (Melhuish TA, Taniguchi K, Wotton D) PLoS One 2016;11(5):e0155837 PMID: 27187787 PMCID: PMC4871493 SCOPUS ID: 2-s2.0-84969799232 05/18/2016. PubMed

[6] Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells. (Taniguchi K, Shao Y, Townshend RF, Tsai YH, DeLong CJ, Lopez SA, Gayen S, Freddo AM, Chue DJ, Thomas DJ, Spence JR, Margolis B, Kalantry S, Fu J, O'Shea KS, Gumucio DL) Stem Cell Reports 2015 Dec 08;5(6):954-962; PubMed

[5] Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway. (Taniguchi K, Anderson AE, Sutherland AE, Wotton D) PLoS Genet 2012;8(2):e1002524 PMID: 22383895 PMCID: PMC3285584 SCOPUS ID: 2-s2.0-84859177990 03/03/2012. PubMed

[4] Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation. (Powers SE, Taniguchi K, Yen W, Melhuish TA, Shen J, Walsh CA, Sutherland AE, Wotton D) Development 2010 Jan;137(2):249-59 PMID: 20040491 PMCID: PMC2799159 SCOPUS ID: 2-s2.0-73649117155 12/31/2009. PubMed

[3] Heterogeneity of Kir4.1 channel expression in glia revealed by mouse transgenesis. (Tang X, Taniguchi K, Kofuji P) Glia 2009 Dec;57(16):1706-15 PMID: 19382212 PMCID: PMC2764821 SCOPUS ID: 2-s2.0-71249101105 04/22/2009. PubMed

[2] Intrinsic and extrinsic light responses in melanopsin-expressing ganglion cells during mouse development. (Schmidt TM, Taniguchi K, Kofuji P) J Neurophysiol 2008 Jul;100(1):371-84 PMID: 18480363 PMCID: PMC2493479 SCOPUS ID: 2-s2.0-51349093447 05/16/2008. PubMed

[1] Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. (Nishioka N, Nagano S, Nakayama R, Kiyonari H, Ijiri T, Taniguchi K, Shawlot W, Hayashizaki Y, Westphal H, Behringer RR, Matsuda Y, Sakoda S, Kondoh H, Sasaki H) Development 2005 Jun;132(11):2535-46 PMID: 15857913 SCOPUS ID: 2-s2.0-21244469465 04/29/2005. PubMed